The Ultimate Age Stop Strategy after 35

Original article can be found on: Mums – in – Hills Blog

To learn more about A.G.E. STOP PRODUCTS please visit:

by Tsitaliya Mircheva

My favourite writer of all times once said: “I don’t believe in ageing, I believe in forever altering one’s aspect to the sun”. I don’t know whether this sentence makes much sense to the modern woman of our time who is more concerned about crease lines, dynamic expression lines and gravitation folds rather than finding her spot under the sun, but for me, I learned quite early on to differentiate beauty from ageing when looking myself in the mirror. Smooth wrinkle-free skin doesn’t necessarily mean beautiful and equally, beautiful doesn’t necessarily mean young or perfectly proportioned.

What I always strive for when stealing that moment to look in the mirror, is a healthy, vibrant face and body. I strive towards a refreshed and vital glowing skin and not necessarily perfectly done make up or fuller lips, blow dried hair and chiseled cheekbones. This means that I care a lot more about what’s on my plate and how much I exercise than having the perfect manicure and skincare. Yet, there comes a time when you know that taking care of yourself internally has to be backed up with the proper skincare products, perhaps some supplements and a well groomed look.

And when it comes to skincare, in the times of the beauty cult we live in, it is never easy to choose what’s right. There are so many factors beside what you want for your skin. You need to consider the environment you live in, the seasons and climate change, and even your stress levels. So as much as it is about your self-esteem and how well you think of yourself, it is also about being able to raise your confidence from the outside to the inside: feeling good about the skin you live in.

Once I passed the age of 35 I tried a new product on the market called Age-Stop. Not that I believe that you can stop age, but I do try to keep my mind open, so I tried a product with a fairly impressive list of ingredients on the label, such as Swiss Snow Algae, Royal Epigen P5, Matrixyl® 3000 and Swiss Alpine Plant Stem Cells, which have won numerous international cosmetic awards as the very best ingredients in anti-aging science and skincare.

Two years after I tried the Perfection Concentrate I keep buying it and it turns out it is the one cosmetic line I’ve stayed loyal to for years. The product has now become a best seller worldwide and soon the line will consist of four products, and three more products are being developed as we speak.

In general I don’t have problem skin, so there was no dramatic change, but the way my skin feels is just different and that is enough to convince me. I will, however, not try to convince you but instead pose a few questions to Lilia Bassi, the founder and CEO of Age Stop Switzerland about ageing and how you can support your skin health after 35:

Tsitaliya: How did it happen that you started making your own serum Age-Stop? In other words why did you start producing AGE STOP PRODUCTS.

Lilia Bassi: Since the age of 17 I have had a life – -long ambition of producing my own Skincare line of products targeted towards anti-aging, I have had 3 fails on the way before AGE STOP PRODUCTS products became a Success in Switzerland and World-wide.

Tsitaliya: What is the biggest myth about ageing?

Lilia Bassi: For me the biggest myth about ageing is that genes play the biggest role in how you age. Not true. Even if you’re born with the healthiest set of genes, how you live your life determines how they behave over your lifespan. Your genes can be changed by what you eat, how much physical activity you get, and even your exposure to chemicals.

Tsitaliya: In what way women can slow down the process of ageing of the skin?

Lilia Bassi:

  1. Use SPF
  2. Avoid over-exfoliating
  3. Avoid doing too many conflicting in-salon treatments
  4. Don’t Smoke
  5. Eat lots of Seafood, fruits + vegetables
  6. Avoid drinking Alcohol -it does show on your face after 40
  7. Deep sleep and relaxing massages are important to balance your mind and body which leads to slower ageing process

Tsitaliya: You also are a beauty blogger – for how long, tell us a bit about your story of becoming an entrepreneur?!

Lilia Bassi: I have been blogging for about 4 years. But I have always been an entrepreneur and with my commercial banking background it was only a matter of time until I started on the path of my life -long dream of owning my own Skincare Brand. In short, I have always aspired to be the next Estee Lauder. Blogging was just a way for me to share my knowledge.

None of my blogs are sponsored -hence my viewers value my honesty as I say what I really think of the products I try.

This month you can buy any of the A.G.E. Stop products using the code mumsinheels, which gives you 20 USD discount per product. If you buy two products you will have 40 USD discount or three in a set 60 USD discount.

Skin care products for oily, acne prone skin that deliver visible results

Original article can be found on: Transforming my oily & acne prone skin Blog

To learn more about A.G.E. STOP PRODUCTS please visit:

Skin care products for oily, acne prone skin that deliver visible results

My current skin care regimen is quite something. My skin has never looked better.

I wrote the above sentences yesterday. Today, I can feel a bit of congestion around my nose…

Don’t get me wrong, my skin is most definitely looking at its best these days. But I don’t want to leave you with the impression that all is perfect. Today I noticed the congestion around my nose, the other day I got a new cherry angioma 😦  That’s life.

To be honest, my whole body has been through a lot in the past two-three months, yet my skin not only remained clear of blemishes, but it became more luminous and brighter.

I don’t know if you would be able to relate to this, but my face has never been one uniform colour. The skin around my eyes and my neck are ivory with neutral to yellow  undertones, but the rest of my face has always been a shade of pink due to post inflammation scars and a bit of sun damage. Imagine how difficult it has been to choose the best colour foundation. Do I get one that matches my face, or my neck? I won’t go into that right now. I started telling you about all this because I wanted to share that these days my whole face is the same colour- super calm ivory with neutral to yellow undertones. Also,
1. I’ve had no skin issues before or during my periods.
2. Often times taking new supplements give me a few breakouts, but not this time. I am taking interesting new supplements. I will write about them in a different post.
3. I tried and failed at the Keto diet which apart from  depleting me from electrolytes it didn’t give me any skin rashes or pimples (Thank Goodness!)

So let me share with you the products responsible for my clear, brighter skin:

This is my Morning routine

Step 1 and Step 2

The first product I use after I cleanse my skin is the Mizon AHA and BHA toner.

It is a lovely smelling toner which prepares my skin for the BHA and AHA products. When I first used this toner months ago, I didn’t think it did anything  for my skin and had no plans to repurchase. But since then I’ve learnt that some products work on the skin without making a visible difference.

So how does this toner prepare my skin for the BHA and AHA products that follow?

Apparently for BHA and AHA to work properly they need the right pH. Some people  cleanse their skin, then wait 20 min so that the skin gradually gets to the  “right ” pH and only  then they apply  BHA or AHA products. But  I learnt that I can achieve the right pH quicker by using the Mizon toner. So after I wash my face, I don’t wait around for 20min, I use the Mizon toner straight away and then I apply a BHA or AHA product. Currently I use Cosrx BHA and AHA products.

On most days I  alternate between BHA and AHA products. But occasionally when I have more time, I use one after the other but I wait 20 min between the two applications. 

Step 3

20min after I have applied either the BHA or AHA product, I am ready to use The Body shop Anti-imperfections solution mixed with a couple of drops of Tea tree oil from The Body shop.

The Anti-imperfections solution has a serum-like consistency, it smells of Tea tree oil and it feels cooling and refreshing on the skin. But it leaves the skin sticky. To be honest, I didn’t even notice that it leaves the skin sticky till today, because I apply several more layers of skin care on top and the stickiness disappears.

The reason I mix it with a few drops of Tea tree oil from The Body shop is to make it more powerful for my super oily/acne prone skin. Please note that the Tea tree oil from The Body shop is diluted, it is not pure essential oil, therefore it is super gentle on the skin.

Both products are highly regarded by customers judging from the tons of positive reviews on The Body shop website. I am quite impressed with The Body shop these days, I have bought many products from the Tea tree range and several really good cleansers. I have not included cleansers in this post because I will be writing about them in a separate post later in the week.

This step of applying the Tea tree oil products is crucial for my clear skin. It has taken me a long time to figure out that BHA ( Salicylic acid) alone does not keep my skin clear. BHA unclogs the pores, but it doesn’t get rid of acne bacteria.

In my experience, Tea tree oil deals with the acne bacteria quite well especially when there is not too much of it. What do I mean?

When I had really bad acne ( lots of acne bacteria and clogged pores), neither Tea tree oil nor Salicylic acid worked for me….Now I think that the reason for that was not only the severity of my acne but also the fact that I did not use the two ingredients together.

Based on my experience, I think that my skin remains clear when internally I have my hormones balanced, when I have good digestion and healthy gut bacteria.

Externally, my skin remains clear when my pores are not clogged with oil, keratin or dirt and when acne bacteria is kept to a minimum.

In my experience, Tea tree oil and Salicylic acid on their own are not as effective as they are together. I know there are tons of people for whom only one or the other ingredient has “solved” their skin issues, sadly that is not the case with me. I need to use both ingredients.

Step 4

The next step is the most fun. I apply super potent anti-aging products. I love the a.g.e. stop Switzerland products I use currently because they are improving my skin in several ways. In addition to moisturizing, nourishing, brightening, soothing and smoothing existing wrinkles they stimulate collagen production and improve the elasticity of my skin. I am very interested in all things that stimulate collagen production because I have acne scars which are in essence indentations due to destroyed collagen. If you haven’t read my reviews on a.g.e.stop Switzerland products you really should.

For reviews on the products mentioned in this post see the links below:

To read my review on super gentle Tea tree serum type oil by Manyo Factory click here

To read about the gentle Tea tree oil from The Body shop click here

To read about the daily Anti-imperfections daily solution from The Body shop click here

To read about super effective Tea tree oil cream click here

To read more about the anti-aging products I use click here

To read about why I started using the previously disliked Cosrx BHA and AHA products again click here

To read about the amazing treatment I use for my indented acne scars click here

Till next time, Milu

10 New Anti-Aging Treatments Doctors Swear By in 2017

The article below talks about the latest procedures for skin rejuvenation. To learn about A.G.E. STOP PRODUCTS WHICH CAN BE USED AT HOME TO MAINTAIN YOUR RESULTS, please visit our website:

So you want to look younger? You’re in luck. The new generation of non-surgical youth-boosters—injectables, lasers, and radiofrequency—address small age-related changes over time. Think reducing fine lines as they develop, rather than trying to reverse deep grooves that have been etched for years, so you look like yourself—only younger, says Joshua Zeichner, MD, director of cosmetic and clinical research in the department of dermatology at Mount Sinai Hospital.

They’re also safer, easier, cheaper, and require much less downtime than solutions past. Trouble is, there are so many options out there—seemingly more every week—that it can be tough to know which will give you the most bang for your cosmetic buck. See which top treatments MDs say are worth booking an appointment for now.

Goal: Lift and define your cheekbones and do away with the “parentheses” lines running from your nose to the corners of your mouth
Old option: Going under the knife for an invasive eye lift, face lift, or silicone cheek implants, which can slide out of position
Fresh approach: Juvederm Voluma XC, a dermal filler
Injecting Voluma into the cheekbone area lifts the skin over your cheekbones, which naturally lessens the visibility of nasio-labial folds, and pulls the skin of the lower eye taut, too, to smooth crows feet, says Neal Schultz, MD, a dermatologist based in New York City. And because of the way the gel is made—with fibers arranged in a cross-hatch pattern, as if forming a dense net, it does a better job of padding sunken spots and lasts longer than other fillers: Up to a year or more vs. the six-month duration other fillers offer, adds Schultz. And unlike implants, Voluma will never slip out of place, because the gel incorporates itself into the skin’s layers. “With Voluma, you get a comparable improvement to surgery—without the risks or the costs,” Schultz says.
Good to know: You’ll see the final result before you leave the office, and there’s no downtime. The most common side effects include minor irritation, swelling or redness at the injection site. (Learn how to balance your hormones naturally—and lose weight for life—with the Hormone Reset Diet.)
Sessions: 1; about $1,200

Goal: Plump lips and fill fine vertical lip lines caused by smoking or sucking on a straw
Old option: Injecting lips with lumpy-looking silicone, which may have to be surgically removed later, or newer, heavier fillers that easily over-fill the lips
Fresh approach: Restylane Silk, a dermal filler

You’ve no doubt seen photos of celebs with over-plumped, strangely lumpy pouts; that’s unlikely to happen with this clear gel, which is made of hyaluronic acid, a hydrating substance that occurs naturally in the body, says Rachel Nazarian, MD, a dermatologist with the Schweiger Dermatology Group in New York City. “Because Restylane Silk isn’t thick, it looks natural when placed into fine lines around the lips, an area that’s notorious for getting overfilled,” she adds. Additionally, the filler gets reabsorbed into the skin after about six months, so if you don’t love the look, it will soften on its own.
Good to know: You’ll get immediate results that last around six months, with zero downtime. The filler contains an anesthetic so there’s no need for pre-numbing, and the most common side effect is temporary swelling.
Sessions: 1 or more as needed; about $800 each

Goal: Tone down fine lines at the corners of your eyes and mouth
Old option: Botox, which can stiffen the area, making it harder for you to make normal facial expressions, or heavy fillers that look unnatural
Fresh approach: Belotero Balance, a dermal filler
“Belotero is super thin, allowing me to get closer to the surface to fill in fine lines precisely,” says dermatologist Dennis Gross, MD, a New York City-based dermatologic surgeon and founder of Dr. Dennis Gross Skincare. Two reasons it’s a home run: Unlike Botox injections around the mouth, you’re at no risk of an eerily expressionless face, Gross adds. And the smooth, hyaluronic acid-based gel integrates fully into your own skin tissue, so you’ll never look like you’ve had “work” done.
Good to know: You’ll see immediate line-lessening results that last around six months. There’s no downtime and only a small chance of side effects (swelling, bruising, redness, pain, or itching). Plus, a major bonus: fillers made from hyaluronic acid have been shown to spur your skin’s natural wrinkle defense by ramping up collagen production and even preventing existing collagen from breaking down.
Sessions: 1; about $800-$900

Goal: Even skin tone and texture by tackling fine lines, acne scars, and age spots
Old option: Microdermabrasion, a facial in which a spray of tiny crystals physically scrapes off the top layer of skin—out-of-sun recovery is a must
Fresh approach: DermaPen, the only FDA approved micro-needling pen

“DermaPen has a cluster of superfine needles that punch microscopic holes in your skin, triggering a healing response that stimulates collagen and elastin production, and ultimately improves the texture and elasticity of your skin,” says New York City-based plastic surgeon Matthew Schulman, MD. Micro-needling has an edge over microdermabrasion because it encourages new collagen to form. Translation: your skin isn’t just smoother, with smaller pores and fewer brown spots, but it’ll end up firmer, too.
Good to know: The downtime ranges from a few hours to 2 to 3 days depending on how deep your treatment goes—it’s customized to your skin’s needs. Results are cumulative, so your skin gets better each time. Side effects include redness and, with more intense treatments, minor scabbing.
Sessions: 5-6; about $500 each

Goal: Treat active acne and erase past acne scars
Old option: Fraxel and C02 lasers, which can cause swelling, redness, oozing, and peeling that can last more than a week.
Next-Gen:  Regenlite Transform Laser
MD says: One treatment with Regenlite, a laser light held close to the skin, can reduce pimples by 50%, says LA-based plastic surgeon Chia Chi Kao, MD. Like other lasers, it uses light to kill acne-causing bacteria and stimulate collagen growth. The key difference: Regenlite doesn’t use heat, which makes the body race to form scar tissue, leading to skin that looks waxy, shiny, stiff, or fibrous. “If you walk around LA, you’ll see people with this pasty, leathery look from more aggressive laser treatments,” Kao says. “Since Regenlite doesn’t heat the skin, it coaxes cells to make collagen that’s soft and pliable, rather than activating your skin’s emergency inflammatory process and scarring.”
Good to know: No anesthesia is required, and there’s little to no downtime. You’ll see some improvement within days but it can take up to 3 months to see full results, which typically last 9 months.
Sessions: 3-5; about $900 each

Goal: Melt stubborn fat pockets
Old option: Liposuction, which is invasive, causes major pain and bruising and puts you out of commission for two weeks, on average
Fresh approach: UltraShape System, body shaping treatment
“It’s the first and only non-invasive body shaping treatment that uses ultrasound energy to target fat without harming the surrounding skin, nerves, and muscles,” says Dennis Gross, MD. UltraShape works by literally shaking fat cells to death—they break apart and disintegrate before heading to the liver for disposal. Just like liposuction, UltraShape trims stubborn fat on the stomach, thighs, butt, and backs of arms, but since it doesn’t require an incision, there’s no risk of infection and you can be back at work the same day. Ultrashape also edges body shaping lasers, which don’t work on all skin tones, Gross says.
Good to know: There’s no anesthesia, no downtime, and no side effects. Expect visible results—an estimated 2 to 3-inch reduction in circumference—two weeks after your first treatment.
Sessions: 3; about $1,400 each

Goal: Repair sun damage by fading sun spots, smoothing wrinkles, and firming loose skin
Old option: Fraxel or C02 lasers, which can cause swelling, redness, oozing, and peeling for 4 to 10 days…or more
Fresh approach: eMatrix, fractional resurfacing using radiofrequency energy
“I’m using eMatrix to treat sun damage—it makes skin smoother, brighter and tighter,” says Jamé Heskett, MD, founder of The Wellpath in New York City. EMatrix delivers radiofrequency (electrical) energy in a grid-like pattern below the skin’s surface, creating tiny skin injuries that prompt collagen to regenerate. “It’s better than Fraxel or C02 lasers because it works below the skin instead of on the surface, so there’s less pain and less downtime with better results,” Heskett says. “It’s the closest thing to a facelift without surgery and downtime,” she says.
Good to know: You’ll see an improvement after the first session but the full treatment requires five. Effects can last 8 to 10 years, but Heskett recommends a single refresher session once a year for maintenance. Side effects include sunburn-like redness for 2 to 3 days after the treatment.
Sessions: 5; $500 each

Goal: Slim and tighten loose skin on your arms
Old option: Titan, Ulthera, which are painful and yield unpredictable results
Fresh approach: Thermi RF, radiofrequency skin tightening device

Thermi RF uses radio waves to melt fat tissue, which eventually drains from the body when you pee. The heat also stimulates collagen, so your skin contracts and tightens after the fat dissolves. This latest radiofrequency technology tightens loose skin and gets rid of bulges, but unlike pervious models, you can count on it yielding results in most patients, not just a few, says Yael Halaas, MD, board-certified facial plastic surgeon in NYC. Thermi RF can be done invasively, with slim cannulas going under the skin to cook fat cells directly. The treatment can also be done using a device that goes on top of your skin, called ThermiSmooth, but it takes multiple monthly sessions.
Good to know: There’s no downtime and you’ll see some difference immediately; your skin will continue to shrink for 3 to 6 months. The main side effect is localized swelling.
Sessions: 1 for Thermi RF (the invasive treatment), $4,000; 3 for ThermiSmooth (the topical treatment), $350 per session

Goal: Tighten loose skin at the neck and beneath the jawline
Old option: Thermage, which doesn’t work in an estimated one in three patients
Fresh approach: Exilis Elite, radiofrequency body contouring

“This radiofrequency technology is less painful, more effective and more reliable than older ones,” says Neal Schultz, MD, a board-certified dermatologist in New York City. He reports that patients often come to him for Exilis after having Thermage with other doctors and being disappointed with the results. “Exilis works every time to tighten and firm loose skin on the neck and jawline.” The technology works by delivering thermal heat down into the skin’s deep layers, stimulating new collagen production.
Good to know: You’ll see results after two treatments, but Schultz recommends the full three to four, and the look lasts for up to two years. There’s no anesthesia, no downtime, and no side effects.
Sessions: 3-4, about $600-$800 each

Goal: Remove redness, whether it’s from rosacea, broken capillaries, dilated blood vessels, acne, acne scars, port wine stains, or cherry angiomas 
Old School: A combo of fine needle electrocautery (where an electric current passes through a tiny wire to destroy the targeted tissue) and alpha hydroxy acids for broken capillaries, and topical (but slow and less effective) lighteners like hydroquinone, kojic acid, or steroid creams for other pigmentation issues
Next Gen: VBeam Perfecta, pulsed dye laser MD says: “It removes those tiny red vessels and pigment spots that give skin a blotchy appearance,” says Maine-based dermatologic surgeon Vermen M. Verallo-Rowell, MD, founder of VMV Hypoallergenics. The secret sauce: the Vbeam uses intense but gentle bursts of light to selectively destroy problematic blood vessels but not the surrounding tissue. They’re then absorbed into the bloodstream and eventually leave the body as waste.
Good to know: There’s no downtime and side effects are minor—just some redness that subsides within a few hours.
Sessions: 3; about $300-$400 each


















Matrixyl Inside® – 25 Years of of Innovation AWARD

NIGHT MIRACLE CREAM by A.G.E. STOP SWITZERLAND contains Matrixyl Inside® as one of the three ESSENTIAL MIMETIC PEPTIDES proven to effectively combat signs of ageing skin. To learn more about this product please visit our website.

Matrikines: the key to anti-ageing

In 1999, the French Professor Maquart and his team published their first article mentioning “matrikines”. What does this term designate? A matrikine is a small molecule composed of a short sequence of amino-acids, a peptide, derived from the surrounding extracellular matrix and constituting a signal in order to regulate cell activity. Matrikines play an important role in the wound healing process and connective tissue remodeling.

How does it work?

In order to react to their environment or to internal stimuli and regulate their activity, the cells use several clearly defined signalling pathways that will transfer information from the cell surface to the internal effector system, most of the time the genes. Thus, a matrikine peptide can link to a matching cell-surface receptor which is coupled to a transducer to relay information into the cell using various signalling pathways (TGF-β, PI3K for example in the case of collagen-1). So it works like a key and a keyhole. It means that the structure of the matrikine is important. Different matrikines can trigger different messages.

skin matrix macromolecule synthesis

Several peptides stimulating the production of molecules having a primary role in the maintenance of the skin properties have been identified by Sederma Research Laboratories.

What is Matrixyl®?

Matrixyl® is a trade mark of Sederma SAS. It designates an anti-wrinkle active ingredient for cosmetics containing a specific matrikine which cosmetic nomenclature denomination is palmitoyl pentapeptide-4 (palmitoyl pentapeptide-3 before 2006). It contains a peptide of 5 aminoacids linked to a 16-carbon chain for improving the penetration of the molecule through the lipidic structures of the skin.

The history of Matrixyl Inside®

The first member of the Matrixyl Inside® range was Matrixyl® launched by Sederma in 2000. Then, in order to satisfy the increasing anti-ageing market, Sederma launched in 2003 Matrixyl® 3000 based on two peptides: a palmitoyl tripeptide and a palmitoyl tetrapeptide. Finally, in 2012, Sederma launched a different palmitoyl tripeptide under the trade name Matrixyl® synthe’6®. So far, the Matrixyl Inside® range contains three products.

Which one is better?

None! They are all different and perform different efficacy. For example, Sederma has recently demonstrated with ex vivostudies that Matrixyl® 3000 shows great results in repairing photo-aged skin and defragmented collagen network at the level of the dermis. The crow’s feet wrinkles decrease by 33% after applying a cream for two months. Matrixyl® synthe’6®stimulates the synthesis of collagen but also five other major constituents of the skin. The volume of the forehead wrinkles can decrease by 31% until a dramatic smoothing effect in just two months.

All those products underwent extensive research for efficacy and safety, and are patented. Matrixyl®, Matrixyl® synthe’6®and Matrixyl Inside® are trademarks of Sederma SAS.


PhytoCellTec™ Nunatak®

PhytoCellTec™ Nunatak® is a cosmetic ingredient based on stem cells of Saponaria pumila, an Alpine plant that survived the last ice age. This amazing ingredient is present in PERFECTION CONCENTRATE from A.G.E. STOP SWITZERLAND Luxury Swiss Anti-Aging Products.

Saponaria pumila
Saponaria pumila is an extremophile plant of alpine mountains that survived the last ice age by moving to rare ice-free peaks called nunataks. Constantly exposed to cold and high amounts of UV, this plant developed protecting and repair mechanisms that enabled it to adapt to its challenging environment.

Plant stem cells for skin stem cells
The development of the innovative PhytoCellTec™ technology made possible to grow plant stem cells on a large scale. It also became possible to effectively cultivate rare and protected plants like the Saponaria pumila and to make them available for cosmetics for the first time.

The effect
Mibelle Biochemistry was able to show in extensive studies the capacity of PhytoCellTec™ nunatak® to maintain the regenerative potential of human dermal stem cells despite UV. This protective effect led to an increase in skin elasticity, firmness and density already after 4 weeks’ treatment.

Thanks to the PhytoCellTec™ technology, the survival potential of the extremophile Saponaria pumila plant can be transferred to the cells of our skin in order to protect the latter against daily environmental challenges which are the main cause of skin aging.

Protects dermal stem cells against UV stress
Cultures of human dermal stem cells were treated with PhytoCellTec™ nunatak®, while others were left untreated. The cultures were then exposed to UVA and UVB rays. The capacity of the stem cells to grow in colonies and form three-dimensional spheres was then measured. The results showed that UV radiation strongly reduced the number of spheres that were formed. Treatment with PhytoCellTec™ nunatak® was found to protect against irradiation as the sphere number was 35 % higher compared to the unprotected control (figure 1).

Increase of skin density 
The dermal tissue structure of forearms from volunteers with sun-damaged skin was visualized by ultrasonography before and after treatment with PhytoCellTec™ nunatak® (figure 2). In the ultrasonographic images the dermis appears in bright colours, whereas the so-called subepidermal low echogenic band (SLEB) produces dark patches. This SLEB is the result of a disrupted architecture of the dermis and commonly found in aged and photo-damaged skin. Results clearly show, that a 28 days treatment with PhytoCellTec™ nunatak® reduces the SLEB and significantly improves the dermal tissue density.

Increase of skin elasticity and firmness
The effects of PhytoCellTec™ nunatak® on skin elasticity and firmness were demonstrated in a clinical study including 20 volunteers with sun-damaged skin, average age 53.5. A cream with 0.4% PhytoCellTec™ nunatak® was applied to the inner side of their forearms twice daily for 28 days. Results showed a significant increase of both parameters compared to initial conditions. In particular, the increase in firmness was especially high – more than 14 % compared to the placebo after just one month of treatment

PhytoCellTec™ Alp Rose

Both A.G.E. STOP Night Cream and Sleeping Mask contain PhytoCellTec™ Alp Rose (Stem cells from Swiss Alpine Rose) researched, patented and integrated into skincare by Swiss Mibelle Biochemistry. To discover these products – please visit our website

PhytoCellTec™ Alp Rose is a cosmetic ingredient based on stem cells of alpine rose leaves.

The Alpine rose
The alpine rose is a typical Swiss flowering plant from the Alps. It has bright pink blossoms and grows at altitudes up to 3200 m. Its evergreen leaves are especially resistant to high UV radiation and extreme dryness and cold. The sturdy leaves are a shiny green, even once the snow has melted in the spring. This phenomenon is due to the presence of a special protection protein called dehydrin in the leaves of the alpine rose.

Plant stem cells for skin stem cells
For years researchers at Mibelle Biochemistry have investigated the compounds of the alpine rose and its special protective substances, in particular, the water-retaining dehydrin. The innovative PhytoCellTec™ technology has been used to develop a formula from the leaves’ stem cells that treats dry and stressed skin and has been proven to protect skin cells: PhytoCellTec™ Alp Rose.

The effect
Mibelle Biochemistry was able to show in extensive studies that PhytoCellTec™ Alp Rose promotes the vitality and longevity of skin stem cells. It strengthens the skin barrier, providing better protection to the skin against climate-induced stress.

The effect of PhytoCellTec™ Alp Rose combines two important approaches. Using plant stem cells delays skin aging by protecting vital skin stem cells, keeping the skin looking youthful longer, and giving it a better and more vital appearance. At the same time, PhytoCellTec™ Alp Rose protects the skin using special protective ingredients from this extremely resistant alpine plant.

Protects epidermal stem cells from UV stress
Cultures of epidermal stem cells were treated with PhytoCellTec™ Alp Rose, while others were left untreated. The cultures were then exposed to UVA and UVB rays. The colony-forming efficiency (CFE) of the stem cells was then measured. The results showed that UV radiation strongly reduces the cells’ colony-forming efficiency. Treatment with PhytoCellTec™ Alp Rose increased the stem cells’ colony-forming efficiency (vitality) and provided significant protection against UV rays.

Ski holiday study
Twenty-two subjects were treated with an SPF 30 sunscreen formula during their ski holidays (1 week in March, Alps) to test the effect of PhytoCellTec™ Alp Rose in extreme environmental conditions. Sunscreen without the active ingredient was applied to one side of a subject’s face, while the other side was treated with sunscreen containing the active ingredient PhytoCellTec™ Alp Rose. The loss of skin moisture in the face was then measured after another week of treatment at home. The results showed that water loss was reduced by 39% after 2 weeks’ treatment with PhytoCellTec™ Alp Rose. This indicates that PhytoCellTec™ Alp Rose strengthens the skin barrier and makes it more resistant to environmental stresses such as UV, wind, cold temperatures and dryness.

9 Buzzy Beauty Ingredients You Need to Know in 2017

Hyaluronic Acid is present in all A.G.E. STOP PRODUCTS

1. Licorice

Sure, the taste of black licorice can be pretty polarizing, but this herbaceous root has significant benefits when used in skincare, says Eva Scrivo, beauty expert and owner of Eva Scrivo Salons. Not only can it help to prevent hyperpigmentation and even out skin tone, but those with mild rosacea can also find that licorice helps calm inflammation and tone down redness.

2. Probiotics

You might know about probiotics from hearing nutritionists tout the benefits of incorporating them into your diet, but did you know they can also be good for your skin? “Applied topically, they may be beneficial by restricting the growth of harmful bacteria and decreasing inflammation,” says New York-based dermatologist Dr. Hadley King. “This may be particularly helpful for people who tend to be acne- and rosacea-prone.”

3. Ceramides

Ceramide is a waxy lipid (sort of like a fat) that occurs naturally in your skin and acts as a protectant against dryness and other negative factors. But ceramides can also be useful when found in skincare. According to dermatologist Dr. Melanie Palm, these help to maintain skin barrier integrity, particularly in people with irritated, dry, or damaged skin and eczema. These can appear on labels as “phytosphingosine” or “sphingosine.”

4. Algae

That slimy stuff you see floating on streams and lakes might actually be great for your skin. “Algae, which can detoxify the skin, will continue to gain momentum in 2016,” predicts Mariola Barczewska, esthetician at Haven Spa. Some algae, such as Irish moss and the familiar ingredient carrageenan, act not only as binding agents for other potent ingredients in your beauty products, but also as anti-inflammatories with antioxidant benefits. Look for ingredients like “seaweed extract” or “algae exopolysaccharides” to reap its benefits.

5. Dapsone

Ready to get clear skin in 2016? Traditionally used as an antibiotic, dapsone has been shownto be incredibly useful in treating acne and other skin conditions. “Unlike most topical medications for acne, dapsone is surprisingly gentle — it is not irritating or drying to the skin,” says Dr. King. “That makes it great for sensitive skin, and also easier to use during the winter months when our skin tends to be drier.” If your skin has been irritated and angry in the cold weather, ask your dermatologist if dapsone could provide you with some much-needed relief.

6. L-sodium PCA

This plant-based ingredient has been used since the time of the Ancient Egyptians, who used it to increase skin radiance and moisture in the hair. Today, we know that L-sodium PCA “helps to bind moisture to the skin,” according to Scrivo, so it’s an ingredient you’re going to especially want to look out for during these cold winter months.

7. Manuka Honey

“The benefits of honey, especially manuka honey, are in its inherent antimicrobial and healing properties,” says dermatologist Dr. Julia Tzu of Wall Street Dermatology. This sweet ingredient is gradually making its way from all-natural beauty to more mainstream skin care, where its benefits can be found in cleansers, moisturizers, and even cosmetics such as foundations and lipsticks.

8. Zeaxanthin

This carotenoid gives paprika peppers and saffron their bright, characteristic color, and is most commonly known for its presence in carrots. In skincare, however, zeaxanthin has “been popping up all over the place as an antioxidant packed with potency for anti-aging and hydration,” according to Barczewska.

9. Hyaluronic Acid

The Beauty Lab at the Good Housekeeping Institute is a fan of this lightweight hydrating ingredient, which has shown to be effective at retaining moisture and plumping the skin. Cropping up in everything from toners to lip balms to sheet masks, this is one ingredient you’re sure to see everywhere in 2017.